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Question

Posted on: September 10 2014

Best of all, we were asked to prepare a Theralene syrup, how do we handle this best?

Answer

The Theralene   syrup, which used to be on the market, had the following composition    

Composition du médicament THÉRALÈNE sirop

 

      P 5 ml

      p 10 ml

Alimémazine

        2.5 mg

        5 mg

Saccharose

      3.6 g

      7.1 g

Alcool

190 mg

      380 mg

Substance active  :   Alimémazine tartrate

Excipients  : Acide ascorbique, Acide citrique monohydrate, Caramel, Eau purifiée, Éthanol, Framboise Arôme, Glycérol, P-hydroxybenzoate de Méthyle, P-hydroxybenzoate de Propyle,   Saccharose ,   Saccharose   Solution

I suggest to prepare 60 ml. For this we need 30 mg alimemazine three tablets. These are made very finely (possibly with electirsische coffee grinder). 75 ml of water is boils up.  

Take a brown bottle and pour in the bottle 60 ml of water and tick the level on the outer wall of the bottle with a marker.  

The ground powder is rubbed into a mortar with 35 ml of warm water   and then filtered into the bottle. The mortar and the residue on the filter are rinsed with 15 ml of water. The liquid in the bottle is 600 mg of Vit C added and 5 ml of ethanol which was dissolved: Nipagine 70 mg and Nipasol 30 mg. In this mixture 25 g of granulated sugar is dissolved. As aroma may be added banana aroma. 100 à 200 mg? Eventually, the solution is diluted with water to the level of 60 ml.