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Question

Posted on: January 23 2018

Can Pantoprazole (speciality) be processed in a suspension?

Answer

Pantoprazole occurs as an enteric coated tablet. To prepare a suspension, you must grind the tablet (best in electric coffee grinder) and the obtained powder sieves. What remains on the sieve is once again ground and sieved again to remove the remnants of the enteric casing. Given that the enteric envelope is taken away, there is no more protection against gastric tummy and you should follow the method of preparation of the omeprazole suspension. A new composition has been described on the recipe helpdesk for the omeprazole suspension to improve the TMF composition. With the use of NaHCO3 we can try to reduce the acidity of the stomach as well as the breakdown of Pantoprazool.