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Question

Posted on: November 19 2015

A good formula for a suspension with Clioquinol 250 mg/5 ml

for intestinal parasites

Answer

We suggest: clioquinol 5 G; After Saccharinate 50 mg; Citric acid 100 mg; HPMC 100 mg; Nipagine 100 mg; Microcrystalline cellulose   (Avicel RC 581) 2g, Tween 80 0.5 g; Sugar syrup 30 g and freshly boiled purified water up to 100 ml  

Insert in a small mortar successively the powders begin with the smallest quantities; mix after each addition; Rub the powder mixture into the mortar with   0.5 g Tween 80 and 30 g sugar syrup and add slowly under hard stirring 50 ml freshly boiled Water.  

Take a bottle of 100 ml and bring in the bottle 100 ml of water. Mark the level with a marker on the wall of the bottle. Empty the bottle.

Pour the contents of the mortar into the bottle, rinse the mortar twice with 10 ml of warm water and pour the rinse water into the bottle. Apply to volume with freshly boiled   water. An operation of the suspension with a homogenizer is desirable.