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Question

Posted on: March 6 2013

How can I get "REMERGON" 10mg in a capsule processed?

Remergon is still available in Belgi ë only in Solutabs. Hence my problem in prescribing magistal preparations.

Answer

After going through the documentation of the company I noticed that this is a small atmosphere (nonpareilles) laden with active and flavoring and then mixed with filler to allow compression. There are several motives to follow this rather cumbersome technique. They do not seem convincing to me. It is said that the patients do not find this form too formidable. One speaks here also of a melting tablet. But this here is clearly different from eg the Imodium Instant. Remergon tablets are quite easily divided into a powder containing small spheres. I see no problem to prepare starting from such 10 mg tablet capsules. In my opinion, there may be a problem of inhomogeneity because the filler that one will use to lengthen will be finer than the microatmosphere. So the latter must be very well shattered into very fine material. The fact that the coating is broken poses no problem because this coating only has a flavour covering function. After all, mirtazapine is bitter. I hope to have answered your question here.