How can i solve or process tretinoin in next solution?

Neither Minoxidil nor Tretinoin are well soluble in water; it is therefore a matter of finding the appropriate level of alcohol that both products hold in solution. I would therefore leave the alcoholic solution of both medicines + PG and then add very slow water under continuous stirring until a cloudy form is formed. At this moment I add alcohol (e.g. 10 ml) to clear and then dilute again with water and so on to a total volume of 200 ml. It is therefore appropriate to maintain the amount of water and alcohol added in order to allow the final composition Unsubscribe. I suspect adding 4 to 6 g of Tween 80 (solubilisation) might also be able to offer a solution without excessive reduction in the amount of water.