Question
Posted on: March 6 2013How to compound Methoxsalen suppositories from capsules Oxsoralen?
I am a pharmacy intern from Nova Southeastern University and I am currently working at the Drug Information Center in West Palm Beach, Florida. We received a drug information question from a pharmacist in Ponce, Puerto Rico and she wanted detailed instuctions on how to compound Methoxsalen suppositories from capsules Oxsoralen.
Answer in English please.
Answer in English please.
Answer
I am not very familiar with compounding in the US and even less in Puerto Rico! I see only one small problem. 8-MOP might be soluble in the suppository base as it is a lipophilic product. This may result in a decrease of the directional temperature. This all depends on the concentration. But it might be better than expected. Should the suppositories solidify at a temperature below 30 ° C a suppository base with a higher melting point is used.
I hope this will help.
I hope this will help.