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Question

Posted on: March 6 2013

How do I best prepare the following formula: Trimetoprim 300 mg Sir simpl AD 60 ml

Answer

There are two possibilities.

there is on the one hand a trimethoprim beverage with following composition:

Trimethoprim 1 G; lactic acid 0.46 g; muntspritus 1g; water 15 ml and sorbitol solution not crystallizable up to 100 ml.
The bitter taste of the trimethoprim appears to be properly corrected by the sorbitol and peppermint oil. With regard to stability, we suspect no problems given the stability of the injection fluid.

on the other hand, there is also the suspension:

Trimethoprim 1 G; Avicel RC 581 1 g; NaCMC 400 mg; Sorbitol 70% not crystallizable 60g; Nasaccharinate 100 mg, anijssprititus 1.5 g and aqua Conservans up to 100 ml.