To recipes helpdesk

Question

Posted on: May 12 2015

How to prepare next eye ointment with boric acid?

Hypertone Nacl Eye Ointment R/NACL 0.7 g H2O 1.5 g White Vaseline 6.5 g Boric acid 10 mg Processing grain-Free emulsion

Answer

1. The solubility of boric acid is 1 g in +/-20 ml of water so for 10 mg we need 0.2 ml of water. This quantity is in stock.  

2. I compare your composition with another one, which was published on the website: NaCl 5%, water 15%, wool fat 15% and white petroleum jelly 65%   (see question box)  

3. Your composition multiplied by a factor of 10 indicates: NaCl 7, Water 15, White petroleum jelly 65

4. Perhaps we need to adjust your composition within the meaning of point 2: NaCl 0.5   (or 0.7;   can succeed with 0.7 g), water 1.5 g; Wool grease 1.5 g and white Vaseline 6.5 g        

Boric acid 10 mg must be soluble in the water provided. I hope that the solubility does not drastically diminish due to the presence of salt. I think you should test beforehand whether NaCl 0.7 or 0.5 g and boric acid dissolve 10 mg in 1.5 ml of water. You will need to prepare a larger amount (e.g. 10 ml) of this solution and add an aliquot to the sterilized cooled salmon base under mixing through a sterile membrane filter.   Use a graduated syringe.    

The preparation can be performed as described for the composition listed in point 2