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Question

Posted on: March 6 2013

Is it possible to make dithranol washable emulsion as a stock preparation (without dithranol in it), so that we only have to add the dithranol on delivery?

Our formula VR stock preparation:
cetiol V 20.5%
cetomacrogolcr &egave; me 15%
Paraffin liquidum 15%
Salicylic Acid 1%
ascorbic acid 0.05%
Aqua AD 100g

Answer

Of course I don't know how long you want to keep this stock preparation in stock. However, We must take into account that ascorbic acid is not indefinitely sustainable. According to my data, the highest stability is at pH = 6. Injections of ascorbic acid have a pH between 5.5 and 7 after neutralization with NaHCO3. We will certainly sit there because of the presence of salicylic acid. And therefore, is it perhaps safer to add the ascorbic acid along with dithranol?