Magijet prescription from hospital: R/ceftazidime 5% ear drops.

We assume the only available vial of Glazidim with 1 g   Ceftazidim. After reading the package leaflet,     It is clear that this vial contains the active ingredient in powder form but also a certain amount of Na2CO3. I think the latter is necessary to bring ceftazidim   into solution.

  Further, the use of sterile physiologic serum as solvent seems to be accepted and not to give any problems.     You should therefore attach the appropriate volume of physiological serum to the vial with a sterile syringe of 10 ml with sterile needle being 10 ml Physiological serum. If one   now from that solution in the vial 5 ml with the sterile syringe then you have 500 mg ceftazidime. Those 5 ml you transfer into a sterile eyedropper bottle and add 5 ml of sterile physiological serum to it. In the total volume of 10 ml there is 500 mg ceftazidim   being 5%.     Now there is still the problem of stability. At a 5% solution stored at room temperature there is a loss of 35% within the week, kept in the refrigerator 10% loss within the week.     on the other hand, there is a study on a 2% solution where 10% loss occurred after three weeks if stored in the refrigerator.   in principle, the ear drop, stored in the refrigerator, lasts one week. Taking into account the cost of this preparation, I would make a compromise and recommend a use my 14 days with strict   storage of the bottle in the refrigerator.   If the administration of the cold ear drip gives problems, one can let the solution come to a temperature so that the largest cold is out.     The surplus in the vial retention does not make sense because of the very short shelf life.