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Question

Posted on: March 6 2013

Next preparation is prepared starting from Detrusitol retard 4 mg. These are capsules number 3 with Microgranules. How is the preparation best made?

R/Detrusitol Retard 2 mg MFSA capsule < br/>

Answer

To crush and dilute the contents of the capsules with filler is excluded here. However, we could consider diluting the contents of the required number of Gelules not using classic filler as lactose (because of demixing) but with equal parts of blank granules, which have the same size as the medicinal granules. But where to find it??? In fact, I only see 1 solution, which we must admit is not practical and time consuming. This method consists of dividing the weight of the contents of each capsule into two equal weight parts and bringing each part into a capsule. So from 1 capsule of the speciality 2 new capsules are made. A capsule n ° 4 could be used the volume of a N ° 4 is greater than half of a N ° 3. If the doctor can agree to two intakes per day, then it could also be thought of 1 mg of capsules of which 2 per day are taken. In this case, the micorgranules are finely made and filled after dilution to 1 mg/capsule in gelules. This is the method, which I would suggest to the doctor!