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Question

Posted on: April 22 2013

For persistent atopic eczema, "pix" (coal tar) is still prescribed. According to your opinion, which is the most suitable basis please?

Pretreatment hospitalized patients with AD, I previously wrote mostly Pix 3% TCA 0.1% in Paneucerine for Aqua, or with very wet lesions pix 3% TCA 0.1% Zinc oxide 10% in cetyl cream. Do you think propylene glycol is an added value in such preparations?

Answer

I must note that the use of coal tar has decreased over the years due to possible objections to this commodity. In some formularies, compositions are still found.

1. Dermatological Rezepturen  

State coal tar is mixed in 3, 5 and 10% concnetrations in Vaseline, but also in a PEG base (see OJ V)  

2. DAC/NRF  

are compositions, which contain 2.5, 10 and 20%. A Vaseline-free excipiens is used here. For the 2 and 5% the balance is worded as follows: Polysorbate 60 5 G, Miglyol 5 G and Oleum Arachidis hydrogenatum AD 100 g. In   The 10 and 20% no more Miglyol occurs.    

In Belgium is miserably enough oleum Arachidis hydrogenatum not available. An alternative to this could be: white wax 25 g and sweet almond oil 75 g  

3. FNA  

Mentions a samantheorem with either 3 or 5% coal tar in ZnO paste (see TMF)  

The question of whether propylene glycol represents a surplus value, I would rather negatively answer. I suspect that propylene glycol will give rise to dehumanings. My preferred would then go to Polysorbate 60 (possibly 80) as in the DAC/NRF