Question
Posted on: February 5 2015Precipitate diclofenac Na in Emulgel?
Dear
I would like to make Diclofenac Emulgel. I rely on the following formula I found here:
In Voltaren Gel sits 1% diclofenac.
After diclofenac 1g
Isopropanol 21.5%
Propylene glycol 5.5%
Carbopol 980 2%
Liquid Paraffin 10%
Cetomacrogol 1000 3%
Tris or Trometamol 2%
Purified water up to 100 g
This composition gives an Emulsigel.
When making this emulsigel, it always turns pretty white. Voltaren Emulgel is a much more transparent gel, but it contains diclofenac diethylammonium.
Can I conclude by the white colors of the Emulgel that a portion of the Na diclofenac Precipitts back?