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Question

Posted on: March 6 2013

Preparation of epinephrine 1% collyre, assuming epinephrine bitartrate? Buffers?

Answer

I must start by pointing out that epinephrine is little absorbed in the eye. Therefore, I would suggest that you consult the doctor to ask him if he can not agree with the speciality PROLINE. I hope that was not taken from the market??

if it really needs to be prepared, you can animate the composition of "neutralised adrenaline-eye drops":

R/adrenalinebitartrate 1.82 g
Vit C 200 mg
Borax 2.95 g
nametabisulfite 300 mg
phenylmercuriborate 4 mg
Water up to 100 ml
Best ex tempore and keep it in the refrigerator.