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Question

Posted on: March 9 2017

Preparation of a shampoo with LCD, salicylic acid and triamcinolone acetonide,

LCD 10%, triamcinolone acetonide 0.1% Salicylic Acid 5% and shampoo simplex AD 50 ml Hard-to-stir precipitation. Then tried with Cetomacrogol, but cloudy after cooling.

Answer

One can try to solubilize the salicylic acid with Cetomacrogol as well as the substances that precipitate from LCD when diluting with water.

Salicylic acid and triamcinolone acetonide dissolve in molten cetomacrogol 10000; For salicylic Acid 5 grams you need 10 grams of cetomacrogol. Mix with heated shampoo and after cool LCD add
 

An alternative can be the addition of alcohol, a solvent for salicylic acid and triamcinolone acetonide and miscible with LCD. Therefore, I would suggest adding 15 ml of ungenerated ethanol and in the ethanol:   LCD, salicylic acid and triamcinolone acetonide to dissolve and dilute this gradually with shampoo simplex.