Question
Posted on: March 6 2013Some questions about a rectal ointment, the composition is the following: nitrite bismuth base 1.5 g ZnO 1.2 G menthol 0.4 g adrenaline HCl 1:1000 0.45 g cocaine HCl four hundred and fifty
Milligram
lanoline/vaseline AA 18g
lanoline/vaseline AA 18g
S/3 x daily local < BR/> Vraag1: For wholesale only bismuth subnitrate available, can it be used?
Vraag2: Adrenaline HCL would be out of trade, what can be used as an alternative?
VRAAG3: Are there any specifics about total preparation?
VRAAG4: Is there a refund possible, if the adjustment is on prescription?
Answer
Question 1: Nitrite bismuth basically is not known to me as Bismuth subnitrate (basically)
question 2: Adrenaline is a little stable substance and therefore the dry powder is preferable to the solution, which is offered in ampoules packaged. Therefore, it would be better to prepare a trituration 1 on 1000 with mannitol and to process this 450 mg in the ointment;
Question 3: There are no difficulties with this preparation unless that here in this case lanolin = anhydrous wool fat. After all, I do not wish to put water in the ointment to maximize the stability of the adrenaline;
question 3: Coca ï neHCl does not occur in the list of the compensable raw materials. If the doctor can agree a replacement may be done by Lidoca ï ne HCl. Ask him.
question 2: Adrenaline is a little stable substance and therefore the dry powder is preferable to the solution, which is offered in ampoules packaged. Therefore, it would be better to prepare a trituration 1 on 1000 with mannitol and to process this 450 mg in the ointment;
Question 3: There are no difficulties with this preparation unless that here in this case lanolin = anhydrous wool fat. After all, I do not wish to put water in the ointment to maximize the stability of the adrenaline;
question 3: Coca ï neHCl does not occur in the list of the compensable raw materials. If the doctor can agree a replacement may be done by Lidoca ï ne HCl. Ask him.