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Question

Posted on: June 6 2013

There Is an explanation for the instability of next composition with Tretinoin 0.025%, minoxidil 10gram, foam base bassron ad 200ml.

Preparation holds 1 month and foam then becomes liquid. Contacted with Bassron, but they only have info on preparation with only minoxidil. Like your opinion

Answer

There is an incompatibility in the composition. To freshen up the chemical formulas of the constituents.

Tretinoine (vitamin A acid) = the Cocamidopropylbetaine = and is my inssee an "internal" kwaternair amine. I therefore suppose that interaction should be possible with the vitamin A- acid (tretinoin). I currently see a change in the HLB value of this tensio asset. And consequently, it is not surprising that your foam is flowing.