Question
Posted on: February 6 2019Tretinoin soluble in ethanol?
Answer
Tretinoine solution 3,33 g/L
Tretinoin can be in a concentration of 3,33 g/L (or 0.413%) be dissolved in ungenerated alcohol (antiseptic solution). This solution has a density = 0,806 g/ml. Butylhydroxytolua (BHT) is added to this solution at a concentration of 2,67 g/L or 0.33 %.
This solution is suitable for the preparation of Alcohol-aqueous solutions and hydrogels of Tretinoîne as well as packing creams. With alcohol-poor gels and creams, a fine precipitation of Tretinoin is formed.