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Question

Posted on: November 16 2016

In what basis should Methoxsalen be processed?

Patient needs a preparation based on Methoxsalen 0.006%. No idea which ointment base is best for this preparation, both in terms of stability and intended operation (must be applied for PUVA therapy). Already

Answer

R/methoxsalan Alcoholic solution 0.01%     3 G; Base cream   23.5 g; Propylene glycol   4.7 g;   Water up to 50 g

 

 

Alcoholic Methoxsala solution 0.01%: Methoxsala 10 mg; alcohol denat. Up to 100 g                                                                                                  

Base cream:   Glycerol monostearate Type II 4.0 g  ; cetyl alcohol 6.0 g; Miglyol 7.5 g, Vaseline 25.5 g, PEG 400 mono stearate 7.5 g; Propylene glycol 10.0 g; Water up to 100 g  

PEG-400-monostearate will not be available, replace with PEG-1000-Cetylether or Cetomacrogol 1000.