Question
Posted on: March 6 2013Trisenox is an orphan medicine. Therefore quite costly. You happen to have no cooking method for arseentroixide injections?
Answer
(in collaboration with Apoth. M. Dooms)
after trying to meet the following composition: Arseentrioxide 50mg; sodium bicarbonate 25mg and water for injections up to 100ml.
I know the following compound for arsenic rioxide injections 1mg/ml:
arsenic Rioxide 1 mg/mlThis injection is diluted with an infusion. Now if the pH should be 8 then I suspect that Na2CO3 possibly NaHCO3 if base can already be sufficient.
NaOH 1.2 mg/ml
HCl to pH 8
water for injections up to 1ml
after trying to meet the following composition: Arseentrioxide 50mg; sodium bicarbonate 25mg and water for injections up to 100ml.