Question
Posted on: June 30 2016Atropine 0.01% in Solutio pH 4.8 of benzalkonii Chlorido
Answer
The sterilisation methods using heat are more secure in the final receptacle than a sterile filtration. The latter is not excluded. But in your hospital pharmacy you may have a LAF cabinet. This is already a bigger improvement, but the method still gives a certain chance of non-sterility. The total solution is filtered in a pre-sterilized collyrevial
There is no method to prolong the retention period, which imposes the pharmacopoeia for eye drops. The month is counted from the first opening of the bottle. . The short period has to do with the micobiological contamination during use.
Unopen, shielded from light and stored in refrigerator is shelf life 1 year