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Question

Posted on: September 18 2019

Budenoside Syrup-Gel: Formulation for 1mg/10 ml syrup

Ampoules budesonide 1mg/2ml ampoules serve as a source for the budenoside: 60 ml budesonide OPL needed for 300 ml syrup-gel And shelf life?

Answer

I would prepare:

Budenoside Solution 60 ml; Xanthaaangum 6 g; After saccharinate   225 mg; Aspartame 450 mg; After benzoate 560 mg; Glycerin 40 g; Na2EDTA 300mg  ; Citric acid 500 mg; Freshly boiled water up to 300 ml

For the preparation, xanthan gum is first thoroughly mixed with glycerin and then gradually, stirring well, diluted with a part of the freshly boiled water, which was dissolved: after Saccharinate, aspartame, after benzoate, citric acid and Na2EDTA. Add 60 ml budenoside solution and mix. Eventually it is brought to volume. Final homogenisation with rotor-stator homogenizer is recommended.  

The shelf life = 1 month, kept in a cool place.