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Question

Posted on: March 6 2013

A client has read on the Internet (!) a treatment against superior limbic keratoconjunctivitis due to topical use of cyclosporine 0.5 percent droplets. Is this galenic to realize?

Answer

All you can do is leave Neoral capsules and dilute a certain volume solution with sterilized oil to the desired concentration. You may want to use corn oil, which is used for Neoral. Alternatively maybe Miglyol. You can sterilize this oil by heating for 1 hour at 150 ° C in a hot air oven in an aluminium foil covered beaker. The method we used in the lab to sterilize eye ointment base. After sterilization, you can take the volume of the capsule Neoral emptying into the sterilized oil, mix and then fill 10 ml in a sterilized zentrop vial. The rest can be tracked in a sterile vial for later? Of course, work with sterilized material. I suspect this will be an expensive preparation; I do not know if the Health insurance Fund meets: Capsules for oral intake to eye drops?