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Question

Posted on: March 6 2013

Dalacin Vaginal cream costs 22.73 euros for the patient. A doctor will ask me whether we can make that ointment for a patient who often needs Dalacin cream. 40 gram

would cost 9.98 euro. < br/>

Answer

(worked together with pharmacist F. Opsomer)

the pH of the Dalacin cr è me is 5. As a basis the non-ionogenic water-containing CR è me with sorbic acid can be used from the NF. The pH is also 5. Cosmetically, he looks very much like the speciality.

the stability of an aqueous solution of clindamycin HCl is maximally between pH 3-5.5, that of clindamycin phosphate between pH 3.5-6.5. So best clindamycin phosphate use.