How to perform next prescription? Minoxidil 5% alcohol 70 °, 10 g Tween 20 1 G propylene glycol 5 g isopropyl alcohol 20 g Aqua 14 g

In The last addition of NRF is a formula for Minoxidil 5%.

minoxidil 2.5 G br/> Isopropyl palmitate 0.5 g br/> Cremophor RH 40 1.25 g br/> Propylene glycol 7.5 g br/> Ethanol 70 ° to 50 g

For the preparation is a slight warming at 60 ° under cover needed; In the end with ethanol on 50 g bring to replenish the evaporated ethanol. Supposedly Crempophor RH 40 is replaceable by Cremophor EL?

(due to Ap. B. Van Ghyseghem) br/> Cremophor EL as Solubilizer for better in solution keeping minoxidil in a 5% concentration, is a fairly expensive product if sporadically to use. After some tests, the following formula also appears to work:

minoxidil 5% br/> Cetomacrogol 5% br/> Propylene glycol 20% br/> Water 10% br/> Ethanol 96 ° AD 100 cc

Where Cremophor EL was replaced by Cetomacrogol 1000 and the finished solution was retained for 7 days at 4 degrees Celsius. After 7 days of crystallization has not occurred.... br/> Preparation method: Cetomacrogol Melt-add minoxidil and homogenous mixing-add propylene glycol at 60 to 70 degrees stirring to as much as possible dissolved-add mixture of water and ethanol and continue stirring at 60 degrees to a full solution.