Question
Posted on: February 6 2019Methylprednisolone capsules already or not with EC store in the refrigerator?
Answer
For tablets or capsules does not give the Eur Pharm recommendations. But she takes a more flexible stance for the EP, although the dissolution can be faster in EP than AB but it is also being reconstituted.
is satisfied with this standard then can be assumed that the capsules should not be kept in the refrigerator. The USP does not require the preservation of methylpredsnisolon in the refrigerator but requires preserve in tight, light-resistant containers.
The position of the FAMHP Is not unreasonable then the storage in the refrigerator requires the use of a well hermetically closing packing, which Is impenetrable for water vapour (i.e. glass)!.
This is certainly for the enteric coated capsules. After all, CAP is described as: " Cellulose acetate phthalate occurs as hygroscopic" and the atmosphere in a refrigerator is rather moist. Drying Stop capsules can be added.