Question
Posted on: March 6 2013This morning I got a prescription with a preparation for pessaries with Nystatin: Nystatin 100 000e metronidazole 500mg for 5 pessaries
However, < br/> Nystatin is not stable at heat. Should I be able to process more nystatin in such a way that there is still enough product active, but how much?
Answer
I don't think the heat sensitivity of nystatin of that nature is that a temperature of 35 ° C will lead to a grotre breakdown. So Best is to check the temperature of the suppository mass properly and pour the suppositories into a pre-cooled suppository form so that it cools down quickly.