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Question

Posted on: March 4 2016

Preparation 100 ml Diphencyprone 0.001% in acetone

Preparation against alopecia: How to make Trit? Concentrated solution in acetone? How long is this concentrated solution stable?

Answer

The lowest usual concentration is 0.01%   dissolved in acetone. We have to do here with a 10 X more diluted solution so that for 100 ml 1 mg of active substance is needed.  

Taking into account the availability of a sensitive balance, I suggest weighing and dissolving 25 mg of diphencyprone   in 50   ml of acetone   dissolve 250 mg of butylhydroxytolulene in this solution and take   an aliquot of 2 ml. Dilute   to 100 ml. This solution can be used later for the preparation of BV 0.01% solution.  

The concentrated solution should be stored in a bottle completely   wrapped with aluminum foil. Best to store in the refrigerator (deepfreezer)  . Shelf life for 6 months  

The solution, which is delivered to the customer, is also completely coated with all foil. It stores this bottle in the refrigerator