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Question

Posted on: May 13 2016

Preparation Hydrochlorothiazide 5mg/ml solution

The concentration of 5 mg/ml is for paediatric use. Hydrochlorothiazide does not dissolve. How do we obtain a stable preparation, which does not taste too bad as it is intended for a child.

Answer

-I can suggest the following  

Hydrochlorothiazid   0.5 g Saccharose   22.0 g sodium chloride     0.5 g potassium sorbate   0.15 g citric acid Anh.   0.35 g Hydroxyethylcellulose MV   0.6 g

purified water       to                 100 ml    

You can add an aroma like cherry, raspberry, banana?