Question
Posted on: March 6 2013Process a pindolol (metoprolol, Atenolol...) in a suppository or drink. Are there data on stability, shelf life, Excipientia.....?
Answer
As far as the suppository is concerned, we are not able to dispose of the pure raw material with the handicap and we must process all the ballast in the suppository. If this is the case, then perhaps the suppository is preferable to the drink. I suspect little stability problems for suppositories. For liquid forms, it is quite often spoken of preserving the outside influence of the light.
for a drink I can make a few proposals which of course also assumes the pharmaceutical speciality. Caution for the dose when a modified exemption form is used.
- Metoprololtartraat beverage
Metoprolol tablets qs
shelf life: 60 days
Glycerol 40mL
parabens 0.1%
Water up to 100mL
Storage: refrigerator; outdoor influence of light - Atenolol Oral Solution 2 mg per ml
Atenolol tablets 50mg 2
grind the tablets and rub them with the glycerin. Then add the mucus solution.
Glycerol 5ml
parabens 0.1%
Methyl cellulose 1% to 50ml
store at KT.
Shelf life: 60 days