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Question

Posted on: March 22 2017

Should chloroquine phosphate be enteric encapsulated?

It is a mixture of chloroquine phosphate, magnesium and potassium-sparing.

Answer

I take a piece from a publication of a first-class colleague from Germany.  

Enteric coated hard gelatin capsules

Professor Karl THOMA and Karoline BECHTOLD

Capsugel Library

Extract

Enteric coating to improve tolerance

In the case of chloroquine phosphate (38), Bisacodyl (41) and Levodopa (39, 40) The desire, not only to prevent possible irritation, but also to achieve targeted release of the active substance or delayed activity, may necessitate enteric coating.