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Question

Posted on: March 6 2013

Suspension with Disulfiram.

Regularly we have following preparation:
disulfiram 7.5 gram
excipient AD 300ml
with addition of Veegum 4 gram, Aerosil 1.5 gram, Contras. Sugarsir. 100ml water Q.S. and two drops of tween 20 we do not obtain the "ideal" Suspension.

Answer

Use the Cellulose (Avicel RC 581) Dispersion 4% together with 2g Veegum, 100ml sugar syrup and water up to 300ml. From Tween 20 I would take 500mg.