Question
Posted on: August 20 2019Tetracycline mouthrinse Agent
Answer
I would use the following validated Formularium composition: tetracycline HCl 1 g; Nipagine 100 mg, lidocaine 0.5 g; Nacitraat 1.3 G; Propylene glycol 1 g; Sorbitol syrup 65.5 g, xanthan gum 0.5 g and water up to 100 ml
pH 5 à 5.5
Mix in a mortar nipagine and propylene glycol, add lidocaine, rub, and mix with xanthan gum.
Dissolve in a part water Nacitraat
Weigh in a tarred bottle 65.5 g sorbitol syrup and dissolve on tetracycline HCl
Bring in the bottle the contents of the mortar and shake to homogenous
Add the Nacitrate solution in order to save all tetracycline HCl
Weigh the bottle and calculate the hoevelness of residual water
Rinse The mortar with the remaining water and pour the rinse water into the bottle.
Check the final weight = tare + 115 g