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Question

Posted on: March 6 2013

Problems with mouth rinses.

mouthwash I
R/Na bicarbonate 5 g
propylene glycol 10g
Tween 2 G
amylocaine 2 G
myrrhe tincture 5 G
opium tincture 5 G
mint Water AD 100 ml
problem: Before adding tinctures Already slight precipitation! Amylocaine base or is it the Nabicarbonaat that does not completely dissolve?

mouth rinse agent II

R/Na bicarbonate 3 G
borax 5 g
glycerin 10 g
amylocaine 2 G
myrrhe tincture 10 g
opium tincture 10g
mint Water AD 100 ml

Answer

Comment
Both compositions are complicated formulas from the old box! Questions can be asked about the usefulness of Myrrhe and Opiumtinctincture, both of which will cause precipitation with water when diluted. Presumably the preparations are equally efective without myrrhe and opium tincture? In the case of compound I, the observed precipitation is presumably amylocaine base, given the solubility of NaHCO3 is 1 in 10. So basically soluble in the stock quantity of water. This precipitation does not form in composition II given that we obtain a more acidic pH through the formation of Boro glycerin.

method for composition I
bring in a mortar 3 G tragacanth, which is moistened with PG and Tween and add myrrhe and opium tincture and amylocaine HCl. Good rub. Dissolve in 75 ml of water 5 g NaHCO3 (possibly by shaking in a bottle, does not go so easily) and pour that solution slowly and stirring hard in the mortar. Add the required amount of mint spiritus and mix. Transfer into a measuring cylinder and rinse the mortar with the amount of water required to bring to volume.

method for composition II
bring in a mortar 3 G tragacanth, which is moistened with myrrhe and opium tincture. Rub well. Dissolve in 75 ml water 5 g borax and add 10 g glycerin and 2 G amylocaine. After dissolving add 3 G NaHCO3, let react and pour that solution slowly and stirring hard in the mortar. Add the required amount of mint spiritus and mix. Transfer into a measuring cylinder and rinse the mortar with the amount of water required to bring to volume.